3rd Heidelberg International Symposium 
on Diabetic Complications 

6. bis 8.10.2016

The conference will highlight recent exciting developments in key areas of diabetic (long-term) complications, covering a wide range from vascular biology and neuropathology to epigenetics and clinical studies.
We envision contributions allowing the audience to gain an overview of the recent exciting progress on these fundamental topics.

Invited Speakers

Francesco Beguinot|University of Naples|Naples|Naples   
Neil Docherty|University College Dublin|Dublin|Ireland   
Phillipe Froguel|Imperial College London University/ Lille University|London /Lille|UK / France   
Anthony Heagerty|University of Manchester|Manchester|UK   
Stephan Herzig|Helmholtz Zentrum München|Munich|Germany   
Martin Hrabe de Angelis|Helmholtz Zentrum München|Munich/Neuherberg|Germany   
Berend Isermann|University Medical Center Hamburg-Eppendorf|Hamburg|Germany   
Stephan Herzig|Helmholtz Center Munich & Heidelberg University Hospital|Munich/ Heidelberg|Germany   
Berend Isermann|Otto-von-Guericke-University Magdeburg|Magdeburg|Germany   
Rohit N Kulkarni|Czech Academy of Sciences (CAS)|Prague|Czech Republic   
Rohit N Kulkarni|Harvard Medical School|Boston|USA   
George Kunos|National Institutes of Health (NIH) - NIAAA|Bethesda|USA   
Tony Lam|Toronto General Research Institute and Department of Medicine|Toronto|Canada   
Susanne Mandrup|University of Southern Denmark|Odense|Denmark   
Alexander Pfeifer|University of Bonn|Bonn|Germany   
Michael Potente|Max Planck Institute for Heart and Lung Research|Bad Nauheim|Germany   
Matthew Poy|Max-Delbrück-Center for Molecular Medicine (MDC)|Berlin|Germany   
Michael Ristow|ETH Zurich|Zurich|Switzerland   
Alan Saltiel|University of California|La Jolla|US   
Aurelio Teleman|German Cancer Research Center (DKFZ)|Heidelberg|Germany   
Frederic Tessier|Lille 2 University|Lille|France   
Paul Thornalley|University of Warwick|Coventry|UK   
Emmanuel van Obberghen|University of Nice|Nice|France   
Erwin Wagner|CNIO - Centro Nacional de Investigaciones Oncologicas|Madrid|Spain   
Siu Ling Wong|Harvard Medical School|Boston|USA   
Giles Yeo|University of Cambridge|Cambridge|UK   

Nach oben



Program - Thursday, October 6

08.00 - 08.50|Registration 
08.50|Welcome Stephan Herzig, Helmholtz Zentrum München, Institute for Diabetes and Cancer, Munich 
09.00 - 12.30|Session I: Novel concepts derived from clinical studies 
09.00|Essential role of peripheral cannabinoid-1 receptors in type-2 diabetes and diabetic nephropathy George Kunos, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda 
09.30|Prenatal environment and diabetes: possible role of microRNAs
Emmanuel Van Obberghen, Department of Medical Research IRCAN Medical School, Nice 
10.00|Inflammatory links between obesity and diabetes Alan Saltiel, UC San Diego Institute for Diabetes and Metabolic Health (IDMH), La Jolla 
10.30|Coffee break 
11.00|Using iPS cells to interrogate diabetes complications Rohit N Kulkarni, Joslin Diabetes Center- Harvard Medical School, Boston 
11.30|Targeting BAT as a new approach to tackle diabetes Alexander Pfeifer, University of  Bonn, Bonn 
12.00 - 12.30|Short Talks I 
12.00|Reduced glyoxalase 1 activity in carotid artery plaques of non-diabetic patients with increased HbA1c Andreas Peters, University of Heidelberg, Heidelberg 
12.15|Impact of the glyoxalase system on organ development and function under diabetic conditions in zebrafish Elisabeth Lodd, Medical Faculty Mannheim, Heidelberg University, Mannheim 
12.30 - 14.30|Lunch break and poster session Posters are displayed in Foyer 
14.30 - 18.00|Session II: Genetics and Epigenetics of diabetic complications 
14.30|"Genetic susceptibility to diabetes  Philippe Froguel, Imperial College London, London/ Lille University, Lille" 
15.00|New Genetic and Epigenetic insights into Metabolism and Diabetes Martin Hrabe de Angelis, Helmholtz Zentrum München, Institute of Experimental Genetics, Munich/ Neuherberg 
15.30|Genetics of obesity: Can an old dog teach us new tricks? Giles Yeo, University of Cambridge, Cambridge 
16.00|Coffee break 
16.30|Transcriptional networks regulation adipocyte differentiation and function Susanne Mandrup, University of Southern Denmark, Odense 
17.00|The regulatory role of Argonaute2 in glucose and lipid metabolism Matthew Poy, Max Delbrueck Center for Molecular Medicine, Berlin 
17.30 - 18.00|Short Talks II 
17.30|Transforming Growth Factor Beta-like stimulated clone 22 D4 promotes diabetic hyperglycemia and insulin resistance  Bilgen E. Uestuenel, Heidelberg – IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 
17.45|Crosstalk of fatty liver with renal sinus fat impairs renal function and glomerular cell integrity Erwin Schleicher, University of Tuebingen, Tuebingen 
18.00|End of Session



Program - Friday, October 7

08.00 - 08.50|Registration 
09.00 - 12.30|Session III: Emerging concepts in vascular dysfunction 
09.00|Regulation of endothelial quiescence by metabolites Michael Potente, Max Planck Institute for Heart and Lung Research, Bad Nauheim 
09.30|Delayed wound healing in diabetes: The impact of NETs  Siu Ling Wong, Harvard Medical School, Boston 
10.00|Perivascular Adipose Tissue and Arterial Function in Health and Obesity Anthony Heagerty, University of Manchester , Manchester 
10.30|Coffee break 
11.00|Metabolic Stress in the Control of Healthspan Michael Ristow, ETH Zurich, Zurich 
11.30|Proteostasis in diabetic nephropathy Berend Isermann, Otto-von-Guericke-University Magdeburg, Magdeburg 
12.00 - 12.30|Short Talks III 
12.00|Vascular complications associated with gestational diabetic mothers and their newborn Halime Kenar, Kocaeli University, Kocaeli 
12.15|Oxidative stress and biochemical markers of vascular disease in Type 1 diabetes mellitus Jan Skrha, Charles University, Prague 
12.30 - 14.30|Lunch break and poster session Posters are displayed in Foyer 
14.30 - 16.00|Session IV: Organ-Metabolism Crosstalk 
14.30|Impaired methylglyoxal detoxification recapitulates progression of Type 2 Diabetes Aurelio Teleman, German Cancer Research Center (DKFZ), Heidelberg 
15.00|Brain-Liver Axis Tony Lam, Toronto General Research Institute (TGRI), Toronto 
15.30|Inflammation and metabolic dysfunction Erwin Wagner, Spanish National Cancer Research Center, Madrid 
16.00|End of Sessions 
16.00 – 16.30|Coffee break 
16.30 – 17.00|EASD Business Meeting 



Program - Saturday, October 8

08.00 - 08.50|Registration 
09.00 - 12.30|Session V: EASD 
09.00|Glyoxalase 1 inducers - a new treatment for diabetic complications? Paul Thornalley,  University of Warwick, Coventry 
09.30|The liver as a regulator of diabetic complications Stephan Herzig, Helmholtz Zentrum München, Institute for Diabetes and Cancer, Munich 
10.00|Effect of Gastric Bypass Surgery on Experimental Diabetic Kidney Disease Neil Docherty, University College Dublin, Dublin 
10.30 - 11.00|Short  Talk  EASD 
|Dicarbonyl stress in periodontitis – the fifth complication of diabetes Naila Rabbani, University of Warwick, Coventry 
10.45 - 11.00|Coffee break 
10.30 - 11.30|Poster Session EASD Posters are displayed in Foyer 
11.30|AGEs, can we eat diabetes? Frederic Tessier, Lille 2 University, Lille 
12.00|Does Epigenetics account for Diabetes (and Comorbidity) Risk? Francesco Beguinot, Federico II University of  Naples, Naples 
12.30 - 13.30|Farewell